* Elucidating the two-step targeting mechanism of polymer lipid hybrid nanoparticles for shuttling trastuzumab across the blood brain barrier (BBB) to treat brain metastasis of HER2-positive breast cancer Read more
* Blood Brain Barrier (BBB)-Penetrating Polymer-Lipid-Nanoparticles to Deliver Therapeutic Agents for the Treatment of Glioblastoma Multiforme Read more
* Two-Step Targeted Hybrid Nanoconstructs Increase Brain Penetration and Efficacy of the Therapeutic Antibody Trastuzumab against Brain Metastasis of HER2-Positive Breast Cancer Read more
* 3D High-Content Screening of Organoids for Drug Discovery Read more
* Remotely Controlled 3D-Engineered Scaffolds for Biomimetic In Vitro Investigations on Brain Cell Cocultures. “Alphabioregen HBMP-202, Alphabioregen HBMP201-F, Alphabioregen PHM001, Alphabioregen AGPM-03” Read more
* BLOOD-BRAIN BARRIER-PENETRATING NANOTHERANOSTICS FORACUTE AND CHRONIC NEURODEGENERATIVE DISEASES AND THE LIKE FIELD OF THE INVENTION Read more
* Blood–brain barrier genetic disruption leads to protective barrier formation at the Glia Limitans Read more
* Validation and characterization of a novel blood–brain barrier platform for investigating traumatic brain injury Read more
* Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate “human brain microvascular endothelial cells; Alphabioregen #ALHE02 were grown in endothelial basal medium” Read more
* Assessing the effect of protein corona formation in the process of EV surface engineering Read more
* A Novel Patient-Personalized Nanovector Based on Homotypic Recognition and Magnetic Hyperthermia for an Efficient Treatment of Glioblastoma Multiforme Read more
* Targeted Inhibition of GATA-3 by Pyrrothiogatain: Implications for Adipocyte Biology and Inflammatory Response” AlphaFBS-HI” Read more
* Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate “HBMEC human brain microvascular endothelial cells; Alphabioregen, #ALHE02” Read more
* Propionic acid induces mitochondrial dysfunction and affects gene expression for mitochondria biogenesis and neuronal differentiation in SH-SY5Y cell line Read more
* In vitro grafting of hepatic spheroids and organoids on a microfluidic vascular bed “Human primary RFP-labeled HUVECs (Alphabioregen, #RFP4) ” Read more
* Single-cell analyses identify circulating anti-tumor CD8 T cells and markers for their enrichment Read more
* Desert Hedgehog-Driven Endothelium Integrity Is Enhanced by Gas1 (Growth Arrest-Specific 1) but Negatively Regulated by Cdon (Cell Adhesion Molecule-Related/Downregulated by Oncogenes) Read more
* Discrimination of glioma patient-derived cells from healthy astrocytes by exploiting Raman spectroscopy “Healthy human brain astrocytes (Alphabioregen) were instead cultured on Petri dishes previously treated with a specific coating for astrocytes (Alpabio Coat, Alphabioregen) with Astrocytes Growth Medium (Alphabioregen)” Read more
* The brain-penetrant cell-cycle inhibitor p28 sensitizes brain metastases to DNA-damaging agents BBB Read more
* Combining Human Organoids and Organ-on-a-Chip Technology to Model Intestinal Region-Specific Functionality Read more
* Prazoles Targeting Tsg101 Inhibit Release of Epstein-Barr Virus following Reactivation from Latency Read more
* Immunomodulatory Effect and Bone Homeostasis Regulation in Osteoblasts Differentiated from hADMSCs via the PD-1/PD-L1 Axis Read more
* Single-cell analyses identify circulating anti-tumor CD8 T cells and markers for their enrichment Read more
* Surface functionalization of extracellular vesicle nanoparticles with antibodies: a first study on the protein corona “variable”† Read more
* An Ancestral Retrovirus Envelope Protein Regulates Persistent Gammaherpesvirus Lifecycles Read more
* Blood–brain barrier genetic disruption leads to protective barrier formation at the Glia Limitans Read more
* Flavagline synthetic derivative induces senescence in glioblastoma cancer cells without being toxic to healthy astrocytes Read more
* SIRT1 promotes lipid metabolism and mitochondrial biogenesis in adipocytes and coordinates adipogenesis by targeting key enzymatic pathways. Read more
* A Miniaturized Pump Out Method for Characterizing Molecule Interaction with ABC Transporters Read more
