Protein G binds to most IgG subclasses from human (human IgG1, IgG2, IgG3, IgG4), mouse (mouse
IgG1, IgG2a, IgG2b, IgG3) and rat (rat IgG1, IgG2a, IgG2b, IgG2c) species. It can binds strongly to goat
(total Ig, IgG1, IgG2), sheep (total Ig, IgG1, IgG2), cow (total Ig, IgG1, IgG2). Protein G can bind slightly
with total Ig from rabbit, dog, cat, pig and guinea pig.